VMware vShield is a suite of security virtual appliances built for VMware vCenter Server integration. The central component in this solution is the vShield Manager.
The vShield Manager is the centralized network management component of vShield, and is installed as a virtual appliance on any ESX host in your vCenter Server environment. A vShield Manager can run on a different ESX host from your vShield agents. Using the vShield Manager user interface or vSphere Client plug‐in, administrators install, configure, and maintain vShield components.
One of the VMware vShield components is VMware vShield Endpoint. vShield Endpoint delivers an introspection‐based antivirus solution. vShield Endpoint uses the hypervisor to scan guest virtual machines from the outside without a bulky agent. vShield Endpoint is efficient in avoiding resource bottlenecks while optimizing memory use. vShield Endpoint installs as a hypervisor module and security virtual appliance from a third‐party antivirus vendor (VMware partners) on an ESX host.
VMware is collaborating with leading security vendors such as McAfee, Symantec and Trend Micro to integrate and deliver full endpoint protection solutions based on VMware vShield.
More information from Trend Micro can be found here.